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The Role of Genes in Obesity

sure many parents who are obese have been raised at some point if the disease will also affect their children. Is genetics a factor? Can we do something about it or have to take the inevitable?

Fathers and mothers should be aware and take the errors committed in their diet and lifestyle to avoid transferring their children, because the key focuses on "eat better and move more."

parents did obese children obese?
When parents are obese or one of them is likely their children are obese increases. In fact, it is estimated that children have between 50% (if one of the parents is obese) and 80% (if both are) likely to be too, yes, considering that genetics is not a factor decisive.

To understand better, even considering that certain genes predispose to this disease, if we do not add other factors such as lack of exercise or poor diet rich in fats or sugars in most cases obesity is not develop.

Consider the role of genes and the latest scientific developments in this regard.


Latest scientific studies about the role of genes in the development of obesity are constant, although there is still much research and learning. Most important of all the known so far is that it opens up new avenues of treatment to consider genes individually. This allows further identify, if possible, their therapy and that it is more effective.
obesity genes
In the development of obesity, as well as the influence of known factors (diet, exercise, socio-cultural factors, etc.), Another element to consider is the individual's genetic profile. In fact, it is clearly demonstrated that genes involved in hunger center in weight regulation in the number and size of adipocytes and fat tissue distribution in different parts of the body as well as in energy expenditure.

is sensed that the energy balance of a person can be influenced by up to 40% of their genetic heritage, affecting your appetite and your metabolism and body composition. For the moment only have been detected some of the genes involved in the onset of obesity, since it is possible that their number exceeds the figure of 25,000. Some of the genes most studied in recent years include: leptin (obese gene-Ob-) and its receptor (diabetes gene-DB-), molecules involved in adipocyte differentiation and lipid transport (PPAR, Rev 2) and adrenergic receptors (ADR 2 and 3), among others. What is the practical application of all this? To get a clearer picture has been shown that alteration of the beta 3 adrenergic receptor gene, causing the person fattening do not exercise regularly.

In this case the treatment should be based on physical exercise, more so than on the actual diet. On the other hand, people do not assimilate all nutrients equally by our genetic base, ie differently assimilate proteins, carbohydrates and fats. Therefore, if we know that genetic information could be recommended to every person confined to a lesser or greater extent an intake of these nutrients, because the one you harm against the treatment of obesity. In fact, those who suffer from a mutation in the PPAR gene, should limit fat intake over the rest of therapeutic considerations.

Other examples of genetic defects are those affecting the center of hunger and satiety located in our brain. Such is the case of Prader-Willi syndrome, a genetic disease that causes the person an insatiable hunger and extreme obesity in childhood. Other genetic syndromes recognized in the today are Bardet-Bield, Cohen and Alström-Hallgren, among others. In this context, it opens a wide horizon for the future development of gene therapy for obesity. A promising future, because if obesity is caused by absence or deficiency of certain genes, the incorporation of a gene or DNA fragment will remedy the existing defect.

Obesity, how to avoid it?
Progress on obesity are constant, while our effort and motivation are still the most effective weapon to defeat it. In fact, the most reasonable solution is still diet and exercise, with a culture change that involves learning to eat better and move more, and reducing calorie intake permanently.

Children learn by imitating everything that surrounds them, especially the family. Therefore, if you want to prevent your children from developing obesity, as a parent you should take as a first step "to discover the mistakes that you make in diet and lifestyle." This requires that you report what causes that lead to obesity, to analyze the problems and seek solutions using strategies or resources needed and to seek assistance when necessary to qualified professionals.

sooner you act the better

face obesity has to act as soon as possible to prevent major difficulties and more permanent. In fact, it was shown that if the child is overweight between 6 months and 7 years old, has a 40% chance of being an obese adult, whereas if it occurs between 6 and 13 years the possibility increases to 70%.

Source: consumer.es

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